Years: 2012 -
Home ground: Sydney Showgrounds and Manuka Oval
First game: Round 13, 2012 at MCG
| Wins | Draws | Losses | % |
| 9 | 0 | 9 | 50.00 |
The AFL's 18th team first competed in the TAC Cup underage competition in 2010. In 2011, they made their senior debut in the pre-season NAB Cup before playing out the season in the North Eastern Australian Football League.
Before their entry to the competition in 2012, Greater Western Sydney sparked a media frenzy when media outlets reported they were set to sign former number one draft pick Tom Scully. After conjecture throughout the 2010 season about his playing future Scully eventually opted to accept a multi-million dollar offer to play for the Giants.
James McDonald joined GWS as a Melbourne-based player mentor in February 2011, and after spending a season playing in the Victorian Amateur competition announced that he would be making a comeback to play with the Giants in 2012. He became the first ex-Demon to appear with the new side.
Ex-Irish import Nicholas Walsh was the Giants' first High Performance Manager in their first AFL season, while former Football Operations Manager Richard Griffiths was named their second CEO.
In Round 4, 2013 Melbourne registered their highest score in a fourth quarter in club history against the Giants, to overturn a 19 point deficit.
Melbourne's first loss to GWS, in their first ever match at the Sydney Showgrounds, proved to be the Giants' only victory for 2013 and in Round 21, 2014 GWS registered their largest ever win to that point and first victory at the MCG with a 64 point win.
Biggest Win
| Margin | Round | Venue | |
| 1 | 78 | Round 13, 2012 | MCG |
| 2 | 67 | Round 5, 2022 | MCG |
| 3 | 45 | Round 23, 2018 | MCG\ |
| 4 | 41 | Round 4, 2013 | MCG |
| 4 | 31 | Round 4, 2013 | MCG |
| 5 | 26 | Round 23, 2015 | Docklands |
| 6 | 25 | Round 21, 2012 | Manuka Oval |
| 7 | 5 | Round 17, 2020 | Gabba |
| 8 | 2 | Round 1, 2016 | MCG |
Highest Score
| Score | Round | Venue | |
| 1 | 22.12.144 | Round 4, 2013 | MCG |
| 2 | 20.15.135 | Round 13, 2012 | MCG |
| 3 | 19.6.120 | Round 5, 2022 | MCG |
| 4 | 15.13.103 | Round 23, 2015 | Docklands |
| 5 | 15.12.102 | Round 23, 2018 | MCG |
| 6 | 12.15.87 | Round 19, 2013 | Sydney Showground |
| 7 | 11.8.84 | Round 21, 2012 | Manuka Oval |
| 8 | 12.8.80 | Round 1, 2016 | MCG |
| 9 | 12.7.79 | Round 17, 2020 | Gabba |
| 10 | 10.8.68 | Round 10, 2019 | MCG |
Biggest Loss
| Margin | Round | Venue | |
| 1 | 64 | Round 21, 2014 | MCG |
| 2 | 45 | Round 2, 2015 | Manuka Oval |
| 3 | 37 | Round 19, 2013 | Sydney Showground |
| 4 | 35 | Round 20, 2017 | Manuka Oval |
| 5 | 32 | Round 3, 2014 | Sydney Showground |
| 6 | 26 | Round 10, 2019 | MCG |
| 7 | 9 | Round 16, 2021 | MCG |
| 8 | 2 | Round 16, 2023 | Traeger Park |
| 8 | 2 | Round 20, 2024 | MCG |
Lowest Score
| Score | Round | Venue | |
| 1 | 3.16.34 | Round 21, 2014 | MCG |
| 2 | 5.15.45 | Round 16, 2023 | Traeger Park |
| 3 | 7.5.47 | Round 3, 2014 | Sydney Showground |
| 4 | 8.8.56 | Round 2, 2015 | Manuka Oval |
| 5 | 10.2.62 | Round 20, 2017 | Manuka Oval |
| 6 | 10.8.68 | Round 10, 2019 | MCG |
| 7 | 12.7.79 | Round 17, 2020 | Gabba |
| 8 | 12.8.80 | Round 1, 2016 | MCG |
| 9 | 11.8.84 | Round 21, 2012 | Manuka Oval |
| 10 | 12.15.87 | Round 19, 2013 | Sydney Showground |
Shared players
2010s
Tomas Bugg
Sam Frost
James McDonald
Tom Scully
Dom Tyson
2020s
Toby Bedford
Jesse Hogan
Braydon Preuss
Adam Tomlinson
AFLW
First game: Round 5, 2017 at Blacktown
| Wins | Draws | Losses | % |
| 6 | 0 | 1 | 85.71 |
Biggest Win
| Margin | Round | Venue | |
| 1 | 77 | Round 2, 2023 | Manuka Oval |
| 2 | 39 | Round 5, 2019 | Blacktown |
| 3 | 37 | Round 6, 2022 | Casey Fields |
| 4 | 16 | Round 6, 2024 | Princes Park |
| 5 | 6 | Round 1, 2018 | Casey Fields |
| 6 | 3 | Semi Final 2020 | Sydney Showgrounds |
Highest Score
| Score | Round | Venue | |
| 1 | 15.9.99 | Round 2, 2023 | Manuka Oval |
| 2 | 8.9.57 | Round 5, 2019 | Blacktown |
| 3 | 7.3.45 | Round 1, 2018 | Casey Fields |
| 4 | 6.8.44 | Round 6, 2022 | Casey Fields |
| 5 | 6.5.41 | Round 6, 2024 | Princes Park |
| 6 | 4.5.29 | Semi Final 2020 | Sydney Showgrounds |
| 7 | 1.9.15 | Round 5, 2017 | Blacktown |
Biggest Loss
| Margin | Round | ||
| 1 | 5 | Round 5, 2017 | Blacktown |