1999 Pre-Season Draft
| Selection | Player | From | Games |
| 8 | Troy Simmonds | Box Hill | 40 |
Pre-Draft Trades
Stephen Powell from Footscray for selection 35 (Patrick Wiggins)
Matthew Bishop to Port Adelaide for selection 42
Troy Longmuir to Fremantle for selection 19 and 63
Melbourne lost their first round selection to Fremantle as a penalty for salary cap rorting. They forfeited the selection to Fremantle as compensation for signing Jeff White. The Dockers used Pick 5 to draft Leigh Brown.
Michael Clark was a father/son pick. Clark was the son of Denis Clark
1999 National Draft
| Selection | Player | From | Games |
| 19 | Brad Green | Tasmania U18 | 254 |
| 20 | Paul Wheatley | Preston U18 | 135 |
| 42 | Michael Clark | Eastern U18 | 1 |
| 50 | Matthew Whelan | Woodville-West Torrens | 150 |
| 63 | Shannon O'Brien | Gippsland U18 | 0 |
| 64 | Cameron Bruce | MHSOB/Melbourne Reserves | 224 |
1999 Rookie Draft
| Selection | Player | From | Games |
| 3 | Mark Bradly | Melbourne | 0 |
| 19 | Luke Taylor | Melbourne | 0 |