This draft provided a high level of quality, albeit without the quantity. Scott Thompson has gone on to be a club leader and almost a top line midfielder. Darren Jolly has since become one of the best ruckmen in the comp and a premiership player. Unfortunately, none of these exploits occured at the Melbourne football club.
2000 AFL Pre-Season Draft (Before 2000 season)
| Selection | Player | From | Games |
| 3 | James Cook | Footscray | 3 |
| 11 | Steven Pitt | Norwood | 5 |
| 14 | Simon Godfrey | Melbourne Reserves | 105 |
The Demons lost their second and third round picks for salary cap rorts during the 1990's. They were initially penalised by losing their first choice as well but the penalty was reduced.
2000 AFL National Draft (After 2000 season)
| Selection | Player | From | Games |
| 16 | Scott Thompson | Port Adelaide | 39 |
| 62 | Daniel Breese | Eastern U18 | 0 |
| 73 | Ross Funcke | North Ballarat | 13 |
| 80 | Mitchell Craig | Eastern U18 | 0 |
2000 AFL Rookie Draft
| Selection | Player | From | Games |
| 15 | Kevin Devine | Ireland | 0 |
| 31 | Darren Jolly | North Ballarat | 48 |
| 46 | Mark Berts | Palmerston | 0 |
| 58 | Benjamin Doherty | Brisbane | 0 |
| 64 | Thomas Marshall | Tassie Mariners | 0 |
Rookie Elevation
Troy Broadbridge