Captain - Coach: Percy Wilson
Finishing Position: 6th
Best and Fairest: n/a
Leading Goalkicker: Harry Harker (47)
Best First Year Player: n/a
Members: 397
| Matches | Ladder | Playing List | |||
Ex-Collingwood champion Percy Wilson was appointed Melbourne's captain-coach in an attempt to boost the team into the finals for the first time since 1915, and while they finished two games out of the four it was a significantly improved performance compared to 1920 when they had fired early then fallen apart for the rest of the year.
Two factions vied for control of the club at the start of the year - the 1920 committee of Harry Parkin, Vin Coutie, L. Nichols, G. Pope, Wally Sykes, G. Couttar and C. Couchman were challenged by a reform group of HD Westley, C. Finlay, K. Batten, C. Brady, H. Ritchie and GH Watson. G. Strickland ran as an independent candidate.
1921 was the first time scores from other grounds were displayed at each match, with codes to decipher the scores available in the Football Record.
The Round 5 match against St Kilda ended in a protest which claimed Melbourne had been wrong given a point and should have lost. Unlike St Kilda's Round 1, 1900 win on protest their efforts at getting the result changed were unsuccessful.
In July Melbourne were scheduled to play a match in Colac but pulled out in the week of the game.
Andrew Manzie and Bill McClelland were Melbourne's delegates to the league.
The player's cricket team began appearing in the Metropolitan League competition at the end of the year.
Practice match
| Opposition | Result | Score | |||
| Melbourne Juniors | ? | ? | |||
Premiership Season
| Round | Opposition | Result | |||
| 1 | Essendon | DRAW | |||
| 2 | Collingwood | LOSS | |||
| 3 | BYE | ||||
| 4 | South Melbourne | WIN | |||
| 5 | St. Kilda | DRAW | |||
| 6 | Richmond | LOSS | |||
| 7 | Fitzroy | WIN | |||
| 8 | Carlton | LOSS | |||
| 9 | Geelong | LOSS | |||
| 10 | Essendon | LOSS | |||
| 11 | Collingwood | WIN | |||
| 12 | BYE | ||||
| 13 | South Melbourne | LOSS | |||
| 14 | St. Kilda | WIN | |||
| 15 | Richmond | LOSS | |||
| 16 | Fitzroy | WIN | |||
| 17 | Carlton | LOSS | |||
| 18 | Geelong | WIN | |||
Ladder
| W | D | L | % | P | |
| Carlton | 13 | 2 | 1 | 142.0 | 56 |
| Richmond | 12 | 0 | 4 | 116.1 | 48 |
| Collingwood | 9 | 0 | 7 | 111.9 | 36 |
| Geelong | 9 | 0 | 7 | 106.1 | 36 |
| Fitzroy | 6 | 2 | 8 | 103.9 | 28 |
| Melbourne | 6 | 2 | 8 | 95.4 | 28 |
| South Melbourne | 5 | 1 | 10 | 84.6 | 22 |
| St. Kilda | 4 | 1 | 11 | 77.1 | 18 |
| Essendon | 3 | 2 | 11 | 80.8 | 16 |
Playing List
| Number | Player | Games | Goals | ||
| 1 | Bill Allen | 14 | 5 | ||
| 2 | Joe Flanagan | 8 | 0 | ||
| 3 | Ted Thomas | 12 | 1 | ||
| 4 | Francis Lyon | 1 | 0 | ||
| 5 | Harry Harker | 16 | 47 | ||
| 6 | Herb Matthews | 13 | 6 | ||
| 7 | Mick Anthony | 8 | 0 | ||
| 8 | Charlie Lilley | 13 | 0 | ||
| 9 | Charlie Streeter | 15 | 0 | ||
| 10 | Jack Brake | 3 | 1 | ||
| 11 | John Lord | 14 | 7 | ||
| 12 | Bob Corbett | 6 | 0 | ||
| 13 | Bill Shelton | 2 | 2 | ||
| 14 | Alec Gray | 1 | 0 | ||
| 15 | George Haines | 16 | 22 | ||
| 16 | Clarrie Lethlean | 9 | 0 | ||
| 17 | Bert Chadwick | 15 | 9 | ||
| 18 | Percy Tulloh | 15 | 18 | ||
| 19 | Harry Coy | 15 | 0 | ||
| 20 | Alf Wilson | 8 | 3 | ||
| 20 | George Walker | 1 | 0 | ||
| 21 | Jack House | 14 | 9 | ||
| 22 | Harry Bruce | 7 | 1 | ||
| 23 | Les Boyd | 7 | 1 | ||
| 25 | Percy Wilson | 16 | 8 | ||
| 26 | Enos Thomas | 2 | 1 | ||
| 27 | Bill Lyte | 1 | 0 | ||
| 28 | Alec Farrow | 14 | 5 | ||
| 29 | Les Wallace | 1 | 0 | ||
| 30 | Pat Bourke | 12 | 3 | ||
| 31 | Fred Long | 5 | 0 | ||
| 33 | Alex Ogilvy | 4 | 0 | ||
Seconds
Media
Argus - 23/07/1921
Argus - 25/04/1922
Notes
Bill Lyte is shown as #27 in the Football Records of Round 3, Round 9 and Round 16.